Free Shipping to all UK customers for orders over £25.00
Free Shipping to all UK customers for orders over £25.00
Free Shipping to all UK customers for orders over £25.00
Product Categories
My Shopping Cart
You shopping cart is empty
You may browse our offerings to locate what you're searching for, then put it in your shopping cart.
Polycystic Kidney Disease
By Jinghua Hu , Yong Yu
Usually dispatched within 3 - 5 business days.
£ 60.74
This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies.Key FeaturesExplores the role of cilia in polycystic kidney diseaseFocuses on myriad state-of-the-art methods and techniquesReviews specific mutations integral to this autosomal genetic diseaseIncludes discussions of model systems